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1.

The aged tumor microenvironment limits T cell control of cancer.

Chen, Alex C Y; Jaiswal, Sneha; Martinez, Daniela; Yerinde, Cansu; Ji, Keely; Miranda, Velita; Fung, Megan E; Weiss, Sarah A; Zschummel, Maria; Taguchi, Kazuhiro; Garris, Christopher S; Mempel, Thorsten R; Hacohen, Nir; Sen, Debattama R.

Nat Immunol; 2024 May 14.

Artículo en Inglés | MEDLINE | ID: mdl-38745085

2.

ER Stress in Dendritic Cells Promotes Cancer.

Garris, Christopher S; Pittet, Mikael J.

Cell; 161(7): 1492-3, 2015 Jun 18.

Artículo en Inglés | MEDLINE | ID: mdl-26091029

3.

Tissue-Specific Macrophage Responses to Remote Injury Impact the Outcome of Subsequent Local Immune Challenge.

Hoyer, Friedrich Felix; Naxerova, Kamila; Schloss, Maximilian J; Hulsmans, Maarten; Nair, Anil V; Dutta, Partha; Calcagno, David M; Herisson, Fanny; Anzai, Atsushi; Sun, Yuan; Wojtkiewicz, Gregory; Rohde, David; Frodermann, Vanessa; Vandoorne, Katrien; Courties, Gabriel; Iwamoto, Yoshiko; Garris, Christopher S; Williams, David L; Breton, Sylvie; Brown, Dennis; Whalen, Michael; Libby, Peter; Pittet, Mikael J; King, Kevin R; Weissleder, Ralph; Swirski, Filip K; Nahrendorf, Matthias.

Immunity; 51(5): 899-914.e7, 2019 11 19.

Artículo en Inglés | MEDLINE | ID: mdl-31732166

4.

Successful Anti-PD-1 Cancer Immunotherapy Requires T Cell-Dendritic Cell Crosstalk Involving the Cytokines IFN-Î³ and IL-12.

Garris, Christopher S; Arlauckas, Sean P; Kohler, Rainer H; Trefny, Marcel P; Garren, Seth; Piot, Cécile; Engblom, Camilla; Pfirschke, Christina; Siwicki, Marie; Gungabeesoon, Jeremy; Freeman, Gordon J; Warren, Sarah E; Ong, SuFey; Browning, Erica; Twitty, Christopher G; Pierce, Robert H; Le, Mai H; Algazi, Alain P; Daud, Adil I; Pai, Sara I; Zippelius, Alfred; Weissleder, Ralph; Pittet, Mikael J.

Immunity; 49(6): 1148-1161.e7, 2018 12 18.

Artículo en Inglés | MEDLINE | ID: mdl-30552023

5.

Successful Anti-PD-1 Cancer Immunotherapy Requires T Cell-Dendritic Cell Crosstalk Involving the Cytokines IFN-Î³ and IL-12.

Garris, Christopher S; Arlauckas, Sean P; Kohler, Rainer H; Trefny, Marcel P; Garren, Seth; Piot, Cécile; Engblom, Camilla; Pfirschke, Christina; Siwicki, Marie; Gungabeesoon, Jeremy; Freeman, Gordon J; Warren, Sarah E; Ong, SuFey; Browning, Erica; Twitty, Christopher G; Pierce, Robert H; Le, Mai H; Algazi, Alain P; Daud, Adil I; Pai, Sara I; Zippelius, Alfred; Weissleder, Ralph; Pittet, Mikael J.

Immunity; 55(9): 1749, 2022 Sep 13.

Artículo en Inglés | MEDLINE | ID: mdl-36103861

6.

Defective sphingosine 1-phosphate receptor 1 (S1P1) phosphorylation exacerbates TH17-mediated autoimmune neuroinflammation.

Garris, Christopher S; Wu, Linfeng; Acharya, Swati; Arac, Ahmet; Blaho, Victoria A; Huang, Yingxiang; Moon, Byoung San; Axtell, Robert C; Ho, Peggy P; Steinberg, Gary K; Lewis, David B; Sobel, Raymond A; Han, David K; Steinman, Lawrence; Snyder, Michael P; Hla, Timothy; Han, May H.

Nat Immunol; 14(11): 1166-72, 2013 Nov.

Artículo en Inglés | MEDLINE | ID: mdl-24076635

7.

Cancer metastasis as a non-healing wound.

Deyell, Matthew; Garris, Christopher S; Laughney, Ashley M.

Br J Cancer; 124(9): 1491-1502, 2021 04.

Artículo en Inglés | MEDLINE | ID: mdl-33731858

8.

Sphingosine-1-phosphate receptor 1 signalling in T cells: trafficking and beyond.

Garris, Christopher S; Blaho, Victoria A; Hla, Timothy; Han, May H.

Immunology; 142(3): 347-53, 2014 Jul.

Artículo en Inglés | MEDLINE | ID: mdl-24597601

9.

Host-functionalization of macrin nanoparticles to enable drug loading and control tumor-associated macrophage phenotype.

Sarkar, Biplab; Arlauckas, Sean P; Cuccarese, Michael F; Garris, Christopher S; Weissleder, Ralph; Rodell, Christopher B.

Front Immunol; 15: 1331480, 2024.

Artículo en Inglés | MEDLINE | ID: mdl-38545103

10.

Pharmacological Polarization of Tumor-Associated Macrophages Toward a CXCL9 Antitumor Phenotype.

Enbergs, Noah; Halabi, Elias A; Goubet, Anne-Gaëlle; Schleyer, Kelton; Fredrich, Ina R; Kohler, Rainer H; Garris, Christopher S; Pittet, Mikaël J; Weissleder, Ralph.

Adv Sci (Weinh); 11(15): e2309026, 2024 Apr.

Artículo en Inglés | MEDLINE | ID: mdl-38342608

11.

Highly Active Myeloid Therapy for Cancer.

Fredrich, Ina R; Halabi, Elias A; Kohler, Rainer H; Ge, Xinying; Garris, Christopher S; Weissleder, Ralph.

ACS Nano; 17(20): 20666-20679, 2023 10 24.

Artículo en Inglés | MEDLINE | ID: mdl-37824733

12.

Dual Immunostimulatory Pathway Agonism through a Synthetic Nanocarrier Triggers Robust Anti-Tumor Immunity in Murine Glioblastoma.

Lugani, Sophie; Halabi, Elias A; Oh, Juhyun; Kohler, Rainer H; Peterson, Hannah M; Breakefield, Xandra O; Chiocca, E Antonio A; Miller, Miles A; Garris, Christopher S; Weissleder, Ralph.

Adv Mater; 35(7): e2208782, 2023 Feb.

Artículo en Inglés | MEDLINE | ID: mdl-36427266

13.

Hybrid LNP Prime Dendritic Cells for Nucleotide Delivery.

Das, Riddha; Halabi, Elias A; Fredrich, Ina R; Oh, Juhyun; Peterson, Hannah M; Ge, Xinying; Scott, Ella; Kohler, Rainer H; Garris, Christopher S; Weissleder, Ralph.

Adv Sci (Weinh); 10(33): e2303576, 2023 11.

Artículo en Inglés | MEDLINE | ID: mdl-37814359

14.

Increased targeting of donor switch region and IgE in Sgamma1-deficient B cells.

Misaghi, Shahram; Garris, Christopher S; Sun, Yonglian; Nguyen, Allen; Zhang, Juan; Sebrell, Andrew; Senger, Kate; Yan, Donghong; Lorenzo, Maria N; Heldens, Sherry; Lee, Wyne P; Xu, Min; Wu, Jiansheng; DeForge, Laura; Sai, Tao; Dixit, Vishva M; Zarrin, Ali A.

J Immunol; 185(1): 166-73, 2010 Jul 01.

Artículo en Inglés | MEDLINE | ID: mdl-20511552

15.

Dendritic cell targeting with Fc-enhanced CD40 antibody agonists induces durable antitumor immunity in humanized mouse models of bladder cancer.

Garris, Christopher S; Wong, Jeffrey L; Ravetch, Jeffrey V; Knorr, David A.

Sci Transl Med; 13(594)2021 05 19.

Artículo en Inglés | MEDLINE | ID: mdl-34011627

16.

Dendritic Cells, the T-cell-inflamed Tumor Microenvironment, and Immunotherapy Treatment Response.

Garris, Christopher S; Luke, Jason J.

Clin Cancer Res; 26(15): 3901-3907, 2020 08 01.

Artículo en Inglés | MEDLINE | ID: mdl-32332013

17.

Development of Adamantane-Conjugated TLR7/8 Agonists for Supramolecular Delivery and Cancer Immunotherapy.

Rodell, Christopher B; Ahmed, Maaz S; Garris, Christopher S; Pittet, Mikael J; Weissleder, Ralph.

Theranostics; 9(26): 8426-8436, 2019.

Artículo en Inglés | MEDLINE | ID: mdl-31879528

18.

Recording the wild lives of immune cells.

Pittet, Mikael J; Garris, Christopher S; Arlauckas, Sean P; Weissleder, Ralph.

Sci Immunol; 3(27)2018 09 07.

Artículo en Inglés | MEDLINE | ID: mdl-30194240

19.

TLR7/8-agonist-loaded nanoparticles promote the polarization of tumour-associated macrophages to enhance cancer immunotherapy.

Rodell, Christopher B; Arlauckas, Sean P; Cuccarese, Michael F; Garris, Christopher S; Li, Ran; Ahmed, Maaz S; Kohler, Rainer H; Pittet, Mikael J; Weissleder, Ralph.

Nat Biomed Eng; 2(8): 578-588, 2018 08.

Artículo en Inglés | MEDLINE | ID: mdl-31015631

20.

In vivo imaging reveals a tumor-associated macrophage-mediated resistance pathway in anti-PD-1 therapy.

Arlauckas, Sean P; Garris, Christopher S; Kohler, Rainer H; Kitaoka, Maya; Cuccarese, Michael F; Yang, Katherine S; Miller, Miles A; Carlson, Jonathan C; Freeman, Gordon J; Anthony, Robert M; Weissleder, Ralph; Pittet, Mikael J.

Sci Transl Med; 9(389)2017 05 10.

Artículo en Inglés | MEDLINE | ID: mdl-28490665

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The aged tumor microenvironment limits T cell control of cancer.

ER Stress in Dendritic Cells Promotes Cancer.

Tissue-Specific Macrophage Responses to Remote Injury Impact the Outcome of Subsequent Local Immune Challenge.

Successful Anti-PD-1 Cancer Immunotherapy Requires T Cell-Dendritic Cell Crosstalk Involving the Cytokines IFN-Î³ and IL-12.

Successful Anti-PD-1 Cancer Immunotherapy Requires T Cell-Dendritic Cell Crosstalk Involving the Cytokines IFN-Î³ and IL-12.

Defective sphingosine 1-phosphate receptor 1 (S1P1) phosphorylation exacerbates TH17-mediated autoimmune neuroinflammation.

Cancer metastasis as a non-healing wound.

Sphingosine-1-phosphate receptor 1 signalling in T cells: trafficking and beyond.

Host-functionalization of macrin nanoparticles to enable drug loading and control tumor-associated macrophage phenotype.

Pharmacological Polarization of Tumor-Associated Macrophages Toward a CXCL9 Antitumor Phenotype.

Highly Active Myeloid Therapy for Cancer.

Dual Immunostimulatory Pathway Agonism through a Synthetic Nanocarrier Triggers Robust Anti-Tumor Immunity in Murine Glioblastoma.

Hybrid LNP Prime Dendritic Cells for Nucleotide Delivery.

Increased targeting of donor switch region and IgE in Sgamma1-deficient B cells.

Dendritic cell targeting with Fc-enhanced CD40 antibody agonists induces durable antitumor immunity in humanized mouse models of bladder cancer.

Dendritic Cells, the T-cell-inflamed Tumor Microenvironment, and Immunotherapy Treatment Response.

Development of Adamantane-Conjugated TLR7/8 Agonists for Supramolecular Delivery and Cancer Immunotherapy.

Recording the wild lives of immune cells.

TLR7/8-agonist-loaded nanoparticles promote the polarization of tumour-associated macrophages to enhance cancer immunotherapy.

In vivo imaging reveals a tumor-associated macrophage-mediated resistance pathway in anti-PD-1 therapy.